Published papers
論文
2023年
Akihiro Matsumoto, Takeo Kitazawa, Yuta Hatori, Hiroshi Nakanishi, Chie Watanabe, Tomoya Takashima, Masahiro Murakami. Targeting cellular gaps using Janus nanoparticles containing cationic polymers and surfactant lipids, Drug Discov. Ther., (2022) in press
Yoshihiko Chiba, Yukika Adachi, Yusuke Ando, Shigeki Fujii, Wataru Suto, Hiroyasu Sakai. A lncRNA MALAT1 is a positive regulator of RhoA protein expression in bronchial smooth muscle cells, Life sciences, 64, 313:121289 (2023)
2022年
Hiroyasu Sakai, Yuta Suzuki, Yu Miyauchi, Fumiaki Sato, Yusuke Ando, Risako Kon, Nobutomo Ikarashi, Yoshihiko Chiba, Junzo Kamei, Tomoo Hosoe. Downregulation of Sparc-like protein 1 during cisplatin-induced inhibition of myogenic differentiation of C2C12 myoblasts, Biochemical pharmacology, 64, 204:115234 (2022)
Fumiaki Sato, Atsunobu Sagara, Kaede Tajima, Shotaro Miura, Kenjiro Inaba, Yusuke Ando, Teruaki Oku, Takashi Murakami, Yoshinori Kato, Tetsuro Yumoto. COL8A1 facilitates the growth of triple-negative breast cancer via FAK/Src activation, Breast cancer research and treatment, 194(2):243-256 (2022)
2021年
Y. Chiba, Y. Ando, Y. Kato, M. Hanazaki, H. Sakai. Down-regulation of miR-140-3p is a cause of the interlukin-13-induced up-regulation of RhoA protein in bronchial smooth muscle cells, Small GTPases, (2021) in press
Y. Chiba, Y. Ando, S. Fujii, Y. Miyakawa, W. Suto, J. Kamei, H. Sakai, M. Hanazaki. Down-regulation of miR-140-3p is a cause of up-regulation of RhoA protein in bronchial smooth muscle of murine experimental asthma, Am. J. Respir. Cell Mol. Biol., 64, 138-140 (2021)
村上 正裕, 渡辺 知恵. 経口核酸医薬開発へのアプローチ, BIO Clinica, 36(14), 85-91 (2021)
2020年
A. Matsumoto, S. Murao, C. Watanabe, M. Murakami. Preparation and in vitro tumor growth inhibitory effect of oligo (L-lactate) nanoparticles, Drug Discov. Ther., 14, 296-303 (2020)
安藤 祐介. セマフォリン7Aは血小板CD42bを介して虚血再灌流障害を悪化させる, ファルマシア, 56, 1044 (2020)
Y. Chiba, C. Ueda, N. Kohno, M. Yamashita, Y. Miyakawa, Y. Ando, W. Suto, T. Hirabayashi, F. Takenoya, I. Takasaki, J. Kamei, H. Sakai, S. Shioda. Attenuation of relaxing response induced by pituitary adenylate cyclase-activating polypeptide in bronchial smooth muscle of experimental asthma, Am. J. Physiol. Lung Cell. Mol. Physiol., 319, L786-L793 (2020)
K. Oono, K. Ohtake, C. Watanabe, S. Shiba, T. Sekiya, K. Kasono. Contribution of Pyk2 pathway and reactive oxygen species (ROS) to anti-cancer effects of eicosapentaenoic acid (EPA) in PC3 prostate cancer cells, Lipid in Health and Disease.19, 15 (2020)
2019年
A. Matsumoto, C. Watanabe, M. Murakami, Janus microspheres for enhanced enteral drug delivery: Preparation and orientated attachment to a Caco-2 monolayer. Drug Discov. Ther., 13(6), 343-353, 2019.
Y. Ando, F. Sato, H. Fukunaga, Y. Iwasaki, Y. Chiba, M. Tebakari, Y. Daigo, J. Kawashima, J. Kamei. Placental extract suppresses differentiation of 3T3-L1 preadipocytes to mature adipocytes via accelerated activation of p38 MAPK during the early phase of adipogenesis, Nutr. Metab. (Lond.), 16, 32 (2019)
T. Oku, C. Kurisaka, Y. Ando, T. Tsuji. Identification of human plasma C1 inhibitor as a target protein for staphylococcal superantigen-like protein 5 (SSL5), Biochem. Biophys. Res. Commun., 508, 1162-1167 (2019)
2018年
Watanabe C, Shu GL, Giltiay NV, Clark EA, Regulation of B-lineage cells by caspase-6. Immunol. Cell Biol., 96 (10):1072-1082, 2018.
T. Oku, K. Shimada, H. Kenmotsu, Y. Ando, C. Kurisaka, R. Sano, M. Tsuiji, T. Fukui, T. Tsuji. Stimulation of Peritoneal Mesothelial Cells to Secrete Matrix Metalloproteinase-9 (MMP-9) by TNF-α: A Role in the Invasion of Gastric Carcinoma Cells, Int. J. Mol. Sci., 19, 3961 (2018)
W. Suto, Y. Ando, T. Hirabayashi, F. Fumiko, S. Shioda, J. Kamei, H. Sakai, Y. Chiba. Prostaglandin D₂ Induces Ca2+ Sensitization of Contraction without Affecting Cytosolic Ca2+ Level in Bronchial Smooth Muscle, Int. J. Mol. Sci., 19, 3036 (2018)
2017年
Matsumoto A, Murakami K, Watanabe C, Murakami M, Improved systemic delivery of insulin by condensed drug loading in a dimpled suppository. Drug Discov. Ther. 11(6), 293-299, 2017.
2016年
Akihiro Matsumoto, Satoshi Murao, Chie Watanabe, Masahiro Murakami. Fabrication of Janus particles composed of poly (lactic-co-glycolic) acid and hard fat using a solvent evaporation method. Drug Discov. Ther. 10(6), 307-313, (2016).
Masahiro Murakami, Chie Watanabe. Can colorectal delivery technology provide a platform for enteral oligonucleotide-based therapeutics? Drug Discov. Ther. 10(5), 273-275, (2016).
Y. Ando, T. Oku, T. Tsuji. Platelet Supernatant Suppresses LPS-Induced Nitric Oxide Production from Macrophages Accompanied by Inhibition of NF-κB Signaling and Increased Arginase-1 Expression, PLoS One, 11, e0162208 (2016)
T. Oku, Y. Ando, M. Ogura, T. Tsuji. Development of Splice Variant-Specific Monoclonal Antibodies Against Human α3 Integrin, Monoclon. Antib. Immunodiagn. Immunother., 35, 12-7 (2016)
Y. Ando, T. Oku, T. Tsuji. Platelets attenuate production of cytokines and nitric oxide by macrophages in response to bacterial endotoxin, Platelets, 27, 344-50 (2016)
2015年
Masahiro Murakami, Kazutaka Nishina, Chie Watanabe, Kie Yoshida-Tanaka, Wenying Piao, Hiroya Kuwahara, Yuji Horikiri, Kanjiro Miyata, Nobuhiro Nishiyama, Kazunori Kataoka, Masayuki Yoshida, Hidehiro Mizusawa & Takanori Yokota. Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route. Sci. Rep. 5, 17035-17047 (2015).
Masahiro Murakami, Akihiro Matsumoto, Chie Watanabe, Yu Kurumado, Masashi Takama, Fabrication of porous ethyl cellulose microspheres based on the acetone-glycerin-water ternary system: Controlling porosity via the solvent-removal mode. Drug Discov. Ther. 9(5), 303-309 (2015).
Y. Ando: Analysis of ligands for CD83, a marker of activated immune cells. The proceedings of the Hoshi University 57, 33-40 (2015)
2012年
T. Oku, M. Nakano, Y. Kaneko, Y. Ando, H. Kenmotsu, S. Itoh, M. Tsuiji, Y. Seyama, S. Toyoshima, T. Tsuji. Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin, J. Biol. Chem., 287, 42910-20 (2012)
2008年
C. Watanabe, G. L. Shu, T. Zheng, R. A. Flavell, E. A. Clark: Caspase-6 regulates B cell activation and differentiation into plasma cells through G1 cell cycle entry. Journal of Immunology, 181(10): 6810-6819, 2008
[総説]
S. Richards, C, Watanabe, L. Santos, A. Craxton, EA Clark. Regulation of B cell entry into the cell cycle. Immunological Review, 224: 183-200, 2008
2005年
A. Kumanogoh, T. Shikina, C. Watanabe, N. Takegahara (contributed equally to the work), K. Suzuki, M. Yamamoto, H. Takamatsu, D.V.R. Prasada, M. Mizui, T. Toyofuku, M. Tamura, D. Watanabe, J.R.Parnes and H. Kikutani: Requirement of CD100-CD72 interaction in fine-tuning of B cell antigen receptor signaling and homeostatic maintenance of the B cell compartment. International Immunology, 17(10): 1277-1282, 2005
2002年
A. Kumanogoh, S. Marukawa, K. Suzuki, N. Takegahara, C. Watanabe, E. Ch’ng, I. Ishida, H. Fujimura, S. Sakoda, K. Yoshida and H. Kikutani: Class IV semaphorin Sema4A enhances T cell-activation and interacts with Tim-2. Nature, 419(6907): 629-633, 2002
A. Kumanogoh, K. Suzuki, E. Ch’ng, C. Watanabe, S. Marukawa, N. Takegahara, I. Ishida, T. Sato, S. Habu, K. Yoshida, W. Shi and H. Kikutani: Requirement for the lymphocyte semaphorin, CD100, in the induction of antigen-specific T cells and the maturation of dendritic cells. Journal of Immunology, 169(3): 1175-1181, 2002
C. Watanabe, A. Kumanogoh, W. Shi, X. Wang, T. Yasui, M. Ikawa, M. Okabe, K. Yoshida and H. Kikutani: Enhanced immune responses in transgenic mice over-expressing truncated and soluble forms of the lymphocyte semaphorin CD100/Sema4D.: Leucocyte Typing VII (Eds. D. Mason et.al): 132-133, Oxford University Press Inc., New York, 2002
[総説]
C. Watanabe: The mechanisms of immune regulation by semaphorins. 細胞工学, 21(11), 1298-1303, 2002
2001年
T. Takizawa, C. Watanabe, I. Saiki, Y. Wada, T. Tohma and H. Nagai: Effect of a new antiallergic drug, VUF-K-8788, on infiltration of lung parenchyma by eosinophils in guinea pigs and eosinophil-adhesion to human umbilical vein endothelial cells (HUVEC). Biological & Pharmaceutical Bulletin, 24(10): 1127-1132, 2001
C. Watanabe, A. Kumanogoh, W. Shi, K. Suzuki, S. Yamada, M. Okabe, K. Yoshida and H. Kikutani: Enhanced immune responses in transgenic mice expressing a truncated form of the lymphocyte semaphorin CD100. Journal of Immunology, 167(8): 4321-4328, 2001
X. wang A. Kumanogoh, C. Watanabe, W. Shi, K. Yoshida and H. Kikutani: Functional soluble CD100/Sema4D released from activated lymphocytes: possible role in normal and pathologic immune responses. Blood, 97(11): 3498-3504, 2001
[総説]
C. Watanabe and A. Kumanogoh: Costimulatory signals of CD100 by turning off negative signaling of CD72. 臨床免疫, 36(3): 359-365, 2001
2000年
T. Satoh, E. Tahara, T. Yamada, C. Watanabe, T. Itoh, K. Terasawa, H. Nagai and I. Saiki: Differential effect of antiallergic drugs on IgE-mediated cutaneous reaction in passively sensitized mice. Pharmacology, 60(2): 97-104, 2000
A. Kumanogoh, X. wang, I. Lee, C. Watanabe, M. Kamanaka, W. Shi, K. Yoshida, T. Sato, S. Habu, M. Itoh, N. Sakaguchi, S. Sakaguchi and H. Kikutani: Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions a role of CD40 in regulatory T cell development. Journal of Immunology, 166(1): 353-360, 2001
W. Shi, A. Kumanogoh, C. Watanabe, J. Uchida, X. wang, T. Yasui, K. Yukawa, M. Ikawa, M. Okabe, J. R. Parnes, K. Yoshida and H. Kikutani: The class IV CD100 plays nonredundant roles in the immune system: defectibe B and T cell activation in CD100-deficient mice. Immunity, 13(5): 633-642, 2000
A. Kumanogoh, C. Watanabe, I. Lee (contributed equally to the work), X. Wang, W. Shi, H. Araki, H. Hirata, K. Iwahori, J. Uchida, T. Yasui, M. Matsumoto, K. Yoshida, H. Yakura, C. Pan, J.R. Parnes and H. Kikutani: Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100. Immunity, 13(5): 621-631, 2000
C. Watanabe, A. Kumanogoh, W. Shi, X. Wang, T. Yasui, K. Yoshida and H. Kikutani: Enhanced immune responses in transgenic mice over-expressing the lymphocyte semaphorin CD100. Tissue Antigens., 55(1): 25, 2000
[総説]
C. Watanabe and H. Kikutani: CD40. 接着分子ハンドブック, 秀潤社, 東京: 154-156, 2000.
C. Watanabe and H. Kikutani: CD40L. 接着分子ハンドブック, 秀潤社, 東京: 154-156, 2000.
C. Watanabe and A. Kumanogoh: CD40 and the lymphocyte semaphorin CD100/Sema4D. 臨床免疫, 33(3): 378-383, 2000
1999年
C. Watanabe, T. Satoh, E. Tahara, K. Murakami, K. Hayashi, K. Hase, T. Andoh, Y. Kuraishi, S. Kadota, H. Nagai and I. Saiki: Inhibitory mechanisms of glycoprotein fraction derived from Miscanthus sinensis for the immediate phase responses of an IgE-mediated cutaneous reaction. Biological & Pharmaceutical Bulletin, 22(1): 26-30, 1999
1998年
C. Watanabe, K. Hase, T. Oku, F. Koizumi, S. Kadota, H. Nagai, T. Namba and I. Saiki: Effect of spikelets of Miscanthus sinensis on IgE-mediated biphasic cutaneous reaction in mice. Planta Medica, 64(1): 12-17, 1998
1997年
C. Watanabe, K. Hase, T. Oku, T. Kuraishi, H. Nagai, S. Kadota, T. Namba, I. Saiki: Effect of spikelets of Miscanthus sinensis on experimental atopic dermatitis in mice. Journal of Traditional Medicines,14:261-264, 1997